By Luigi Bolondi
In fresh years, the imaging-based analysis of mass liver lesions has develop into more and more complicated as a result quantity and morphological variability of lesions that glossy imaging concepts are at present in a position to show. If the sensitivity in detection has drastically elevated, characterisation has remained tricky and represents a serious problem for the clinician.
The availability of blood-pool distinction brokers for ultrasound (US), specifically second-generation US distinction brokers in line with perfluorocarbon- or sulfur-hexafluoride-filled microbubbles, and the improvement of contrast-specific software program and applied sciences have spread out new views either for the instant characterisation of any mass lesion detected within the liver and for expanding the sensitivity people within the detection of liver metastases.
Taking under consideration the nice influence of this new know-how on scientific perform, the ecu Federation of Societies for Ultrasound in drugs and Biology (EFSUMB) organised, in January 2004, in Rotterdam, a consensus assembly of specialists with a view to boost instructions for using US distinction brokers within the prognosis of liver illnesses . those instructions, in addition to discussions of additional advances within the medical program of contrast-enhanced harmonic US are offered during this booklet through an the world over popular team of specialists. The e-book represents offers a tremendous place to begin for medical implementation of this new diagnostic procedure.
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Additional info for Advances in Diagnostic Imaging: The Value of Contrast-Enhanced Ultrasound for Liver
Albrecht T, Hohmann J, Oldenburg A et al (2004) Detection and characterisation of liver metastases. Eur Radiol 14(Suppl 8):25-33 15. Solbiati L, Cova L, Kirn V, Tonolini M (2004) Contrast-enhanced sonography is highly reliable and potentially cost-effective for characterizing focal liver lesions initially detected by unenhanced sonography. RSNA, Chicago 16. von Herbay A, Vogt C, Willers R, Haussinger D (2004) Real-time imaging with the sonographic contrast agent SonoVue: differentiation between benign and malignant hepatic lesions.
Atypical hemangioma in segment II with an echo-poor halo. Rapid arterial filling; completed centripetal filling after 2 min. a Baseline, b Arterial phase (17s), c Late phase (137s) Hepatic Adenoma Hepatic adenomas are rare and much more frequent in women  who are taking oral contraceptive medication. Patients with glycogen storage disease, hemochromatosis, and males using anabolic steroids may have an increased risk. Pregnancy may also be a risk factor . There are two types of adenoma: one of bile duct and the other of liver-cell origin.
Typically they also lack portal veins. US, CT, and MR findings frequently are nonspecific. Small adenomas are mostly missed on baseline US, larger ones often show hemorrhage. On baseline US, adenomas may be hypo-, iso- or hyperechoic. Most small adenomas are difficult to detect, as they have the same or similar B-mode characteristic as the surrounding tissue. In CEUS during arterial phase, some small peripheral arteries enhance before the liver tissue, and the tumor is quickly filled. During PV and late phase, the small, isoenhancing tumors disappear within the normal liver tissue.
Advances in Diagnostic Imaging: The Value of Contrast-Enhanced Ultrasound for Liver by Luigi Bolondi